This collection documents the early career of Dr. Green. It consists of incoming letters and class tickets of Green’s from the period 1838-1841 and petitions, drafts of bills, and bills from his period in the General Assembly in the early 1850s-especially relating to an effort to create a state medical board and a vital statistics law. There are also a list of drugs purchased by Green in 1845 and class tickets for UofL Department of Medicine and Bellevue for James O. Green from 1864-66.