The collection of materials from Red Cross Hospital, founded by a group of Louisville's Black physicians contains correspondence, minutes of the board of directors and its committees, and minutes of medical staff meetings. Also included are financial records and patient records. Additional material includes matters relating to administration, fund drives, professional achievement, and integration of Louisville hospitals.

The scrapbooks contain clippings and some correspondence related to the hospital and its business manager/administrator, Houston A. Baker. Fund drives in 1945 and 1948, as well as dedicatory exercises for a new addition to the hospital in 1951, are documented. Microfilmed by the University of Louisville, 1976.